Publications

Advances in zebrafish as a comprehensive model of mental disorders

Published in Depression & Anxiety, 2023

This review discusses the progress in using zebrafish models to simulate human mental disorders, including behavioral characteristics, modeling methods, and the current challenges and future development trends, aiming to provide theoretical support for exploring the mechanisms and treatment strategies of mental disorders.

Recommended citation: Lei Wang#, Fan Liu#, Yimeng Fang, Jiahui Ma, Jiawei Wang, Hua Li, Wei Wu*, Libo Jin*, Da Sun*. Advances in zebrafish as a comprehensive model of mental disorders. 2023, Depression & Anxiety. https://www.hindawi.com/journals/da/2023/6663141/

Improvement in Zebrafish with Diabetes and Alzheimer’s Disease Treated with Pasteurized Akkermansia muciniphila

Published in Microbiol Spectr, 2023

This study demonstrates that pasteurized Akkermansia muciniphila significantly improves both diabetes and Alzheimer’s disease symptoms in zebrafish, offering promising insights for the prevention and treatment of these comorbid conditions.

Recommended citation: Qu, L#; Liu, F#; Fang, Y#; Wang, L.; Chen, H.; Yang, Q.; Dong, H.; Jin, L.; Wu, W.; Sun, D. Improvement in Zebrafish with Diabetes and Alzheimer’s Disease Treated with Pasteurized Akkermansia Muciniphila. Microbiol Spectr 2023 https://journals.asm.org/doi/10.1128/spectrum.00849-23

Advances in Zebrafish for Diabetes Mellitus with Wound Model

Published in Bioengineering, 2023

This review examines the delayed healing of diabetic wounds, explores the use of zebrafish as a model for studying diabetic wound healing due to its distinct stages and imaging advantages, and discusses challenges and strategies for improving this research model.

Recommended citation: Lin, B.; Ma, J.; Fang, Y.; Lei, P.; Wang, L.; Qu, L.; Wu, W.; Jin, L.; Sun, D. Advances in Zebrafish for Diabetes Mellitus with Wound Model. Bioengineering 2023, 10, 330. https://www.mdpi.com/2306-5354/10/3/330

Advances in biomedical functions of natural whitening substances in the treatment of skin pigmentation diseases

Published in pharmaceutics, 2022

This review discusses the therapeutic potential and mechanisms of natural whitening substances like kojic acid and arbutin in treating pigmentation diseases, addressing their advantages over conventional treatments and exploring solutions to challenges in their practical application.

Recommended citation: 10. Fan Liu#, Linkai Qu#, Hua Li#, Jiaxuan He, Lei Wang, Yimeng Fang, Xiaoqing Yan, Qinsi Yang, Bo Peng, Wei Wu, Libo Jin *, Da Sun *, Libo Jin*, Da Sun*, Advances in biomedical functions of natural whitening substances in the treatment of skin pigmentation diseases, Pharmaceutics. [https://www.sciencedirect.com/science/article/abs/pii/S0024320522002788?via%3Dihub](https://www.mdpi.com/1999-4923/14/11/2308)

Advances in microRNA from adipose-derived mesenchymal stem cells-derived exosome- focusing on wound healing.

Published in Journal of Materials Chemistry B, 2022

This paper highlights the clinical potential of adipose-derived mesenchymal stem cell exosomal microRNAs (ADMSC-Exo-miRNA) in wound healing, detailing their roles in modulating immune response, enhancing skin regeneration, and reducing scar formation, thus offering new insights for developing wound treatment strategies.

Recommended citation: Jiahui Ma#, Ling Yong#. Pengyu Lei#, Hua Li, Yimeng Fang, Lei Wang, Haojie Chen, Qi Zhou, Wei Wu, Libo Jin*, Da Sun*, Xingxing Zhang*, Advances in microRNA from adipose-derived mesenchymal stem cells-derived exosome: focusing on wound healing, Journal of Materials Chemistry B, 2022.10.21. https://pubs.rsc.org/en/content/articlelanding/2022/tb/d2tb01987f

Advances in lncRNAs from stem cell-derived exosome for the treatment of cardiovascular diseases

Published in Front Pharmacol, 2022

This mini review systematically explores the role of long non-coding RNAs (lncRNAs) in exosomes from stem cells as promising agents for treating cardiovascular diseases (CVDs), overcoming the limitations of traditional stem cell therapies, and discusses current challenges and future prospects.

Recommended citation: Ma J#, Lei P#, Chen H, Wang L, Fang Y, Yan X, Yang Q, Peng B, Jin L*, Sun D*. (2022). "Advances in lncRNAs from stem cell-derived exosome for the treatment of cardiovascular diseases." Front Pharmacol. https://www.frontiersin.org/articles/10.3389/fphar.2022.986683/full

Codon optimization of chicken β Gallinacin-3 gene results in constitutive expression and enhanced antimicrobial activity in transgenic Medicago sativa L

Published in Gene, 2022

This study successfully expresses codon-optimized chicken Gallinacin-3 in transgenic Medicago sativa, demonstrating its potent antibacterial activity and potential as a probiotic without affecting mouse body weight or intestinal microflora, suggesting its use for developing disease-resistant plants.

Recommended citation: Jin, L# *; Wang, Y.; Liu, X.; Peng, R.; Lin, S.; Sun, D.; Ji, H.; Wang, L.; Zhang, Y.; Ahmad, N. Codon Optimization of Chicken β Gallinacin-3 Gene Results in Constitutive Expression and Enhanced Antimicrobial Activity in Transgenic Medicago sativa L. Gene 2022, 146656! https://www.sciencedirect.com/science/article/abs/pii/S0378111922004759?via%3Dihub

Mechanism of Lignin Degradation via White Rot Fungi Explored Using Spectral Analysis and Gas Chromatography-Mass Spectrometry

Published in BioResources, 2022

This study demonstrates that white rot fungi, specifically Phanerochaete chrysosporium and Pleurotus ostreatus, can effectively degrade alkali lignin, with degradation efficiency dependent on substrate concentration and enzyme activity, leading to the formation of organic acids, esters, and aromatic substances.

Recommended citation: Jin, L., Zeng, G., Chen, H., Wang, L., Ji, H., Lin, S., Peng, R., and Sun, D. (2021). "Mechanism of lignin degradation via white rot fungi explored using spectral analysis and gas chromatography-mass spectrometry," BioResources 16(3), 5494-5507 https://bioresources.cnr.ncsu.edu/resources/mechanism-of-lignin-degradation-via-white-rot-fungi-explored-using-spectral-analysis-and-gas-chromatography-mass-spectrometry/

Effect of Aerobic Exercise as a Treatment on Type 2 Diabetes Mellitus with Depression-like Behavior Zebrafish

Published in Life Sciences, 2022

This study demonstrates that aerobic exercise alleviates depressive-like behavior in zebrafish models of type 2 diabetes mellitus by reducing inflammation and modulating antidepressant biomarkers, supporting its use in treating comorbid depression in T2DM patients.

Recommended citation: Wang, L#; Ma, J#; Wu, W.; Fang, Y.; Liu, F.; Yang, Q.; Hu, X.; Gu, X.; He, Z.; Sun, D *; et al..(2022). "Effect of Aerobic Exercise as a Treatment on Type 2 Diabetes Mellitus with Depression-like Behavior Zebrafish." Life Sciences. 300, 120578. https://www.sciencedirect.com/science/article/abs/pii/S0024320522002788?via%3Dihub

Biological Functions and Applications of Antimicrobial Peptides

Published in Current Protein & Peptide Science, 2022

This review highlights the unique antimicrobial, antifungal, antiviral, antiparasitic, and antitumor properties of antimicrobial peptides (AMPs), their research progress, and discusses the challenges and potential directions for their application due to their effectiveness and lack of resistance.

Recommended citation: Wang, L#; Qu, L#; Lin, S.; Yang, Q.; Zhang, X.; Jin, L*; Dong, H*; Sun, D*. Biological Functions and Applications of Antimicrobial Peptides. Current Protein & Peptide Science, 23, 1–1 https://pubmed.ncbi.nlm.nih.gov/35598243/

Toxic Mechanism and Biological Detoxification of Fumonisins

Published in Toxins (Basel), 2022

Recommended citation: Qu, L#; Wang, L#; Ji, H.; Fang, Y.; Lei, P.; Zhang, X.; Jin, L*; Sun, D*; Dong, H*. Toxic Mechanism and Biological Detoxification of Fumonisins. Toxins (Basel) , 14, 182 https://www.mdpi.com/2072-6651/14/3/182

Shelly Wang

Publications